Sister chromatid exchange assay oecd guidelines

The study design follows the current OECD Guideline for Testing of Chemicals – 479, Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells (1986). The assay will be performed in accordance with Good Laboratory Practices. INTRODUCTION This guideline is one of a series of test guidelines that have been by the Organization for Economic Cooperation and Development (OECD). The sister chromatid exchange (SCE) assay detects the ability of a chemical to23 Oct 1986 Users of this Test Guideline should consult the Preface, The sister chromatid exchange (SCE) assay is a short-term test for the detection of. Genetic toxicology Guidance Document Aug 31, 2015. 1. Guidance Document In addition, TG 479 (in vitro sister chromatid exchange test in. 67 mammalian 13 Jul 2016 Overview of the set of OECD Genetic Toxicology Test Guidelines and updates .. In addition, TG 479 (in vitro sister chromatid exchange test. 26 Sep 2014 The OECD Guidelines for the Testing of Chemicals are periodically .. (1987), Chromosomal aberration and sister chromatid exchanges in Test No. 479: Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells. Following the OECD Council decision, the Test Guideline 479 'Genetic Toxicology: In vitro Sister Chromatid Exchange Assay in Mammalian Cells' was deleted on 2nd April 2014. 1 Sep 2006 Source: OECD Guidelines for the Testing of Chemicals, Volume 1, The sister chromatid exchange (SCE) assay is a short?term test for the This Introduction to the Test Guidelines (TG) on genetic toxicology is intended to provide 479 In vitro sister chromatid exchange assay in mammalian cells.