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Veterinary Record; In Practice; Veterinary Record Case Reports; Veterinary Record Open Hyperadrenocorticism (Cushing's Disease) Explanation of the Disease Hyperadrenocorticism is an excessive production of the hormone Cortisol. Cortisol is stress hormone produced by the adrenal glands which are located near the kidneys. Cortisol is important for the body's response to stress, metabolism of glucose and control of blood pressure. hyperadrenocorticism (cushing's syndrome) is a constellation of clinical findings and biochemical abnormalities caused by chronic overproduction of cortisol by the adrenal cortices. 1, 2, 3, 4 the purpose of this review is to discuss the available diagnostic tests used to distinguish normal dogs from those with hyperadrenocorticism and, once a … hyperadrenocorticism (PDH), a tumor in the 1 Update on Managing Canine Hyperadrenocorticism Figure 2: Hypothalamic Pituitary Adrenal (HPA) axis in a healthy dog. Note - the solid line is the positive feedback (direct release of hormones) and the dotted line represents the negative feedback; (mechanism by which the hormone release is turned off). Diagnosis of hyperadrenocorticism in dogs ABSTRACT: Hyperadrenocorticism is a common condition in older dogs. It arises when feedback mechanisms within the hypothalamic-pituitary-adrenal axis fail, resulting in a chronic excess of blood cortisol. The most common cause of canine hyperadrenocorticism is a microscopic, benign, pituitary gland
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